The young left-hander is a strong candidate for the NL Rookie of the Year Award and will get a chance to build on his case for the honor on Saturday against fellow rookie Casey Kelly and the Padres.
Miley, who has 14 wins this season, has a 2.28 ERA in his last four starts and is coming off a fine outing against the Dodgers that saw him allow only three runs in 6 2/3 innings.
Don't expect the Padres to roll over. They have won three games in a row and seven of their last 10 games. Moreover, Miley lost his only start against the Padres this season, giving up four runs in 7 1/3 innings in that outing. Cameron Maybin (3-for-9), Chris Denorfia (3-for-10) and Jesus Guzman (3-for-6) all have had success against Miley.
As for Kelly, he had trouble at Coors Field in his second start of the season after tossing six shutout innings in his big league debut. Against the Rockies, he allowed two home runs and five earned runs in 5 2/3 innings. He did limit all of his damage to one inning, a seven-run third inning.
"That says a lot about Casey," Padres manager Bud Black said. "He was fine. He wasn't rattled. He kept battling. He just went out there and kept pitching."
After Friday's 6-5 victory, the Padres have defeated the D-backs seven times in a row.
"If you look at the games they beat us, they were very, very good defensively," D-backs manager Kirk Gibson said. "They've got a good mix: driving the ball, good team speed. They're going to force the issue. They're hard for us to play against. We had some trouble with ourselves, as well. They've played good against everybody, not just us."
D-backs: Goldschmidt a late scratch
First baseman Paul Goldschmidt was scratched from Friday's game because of an illness. He did enter the game as a pinch-hitter, grounding out to end the top of the seventh.
The D-backs are 27-25 against the NL West this season, going 15-12 on road and 12-13 in Arizona.
Padres: Street stays sidelined
All-Star closer Huston Street, on the disabled list since Aug. 11 with a strained left calf, is still unable to run and will remain on the DL. Street has missed a total of 53 games because of injury this season.
"He's a little bummed," Black said. "He thought he'd make a quick recovery based on where he was last week. But it's the break to cover a bunt or cover first, that's something that's getting him."
Right-handed pitcher Ross Ohlendorf and catcher Eddy Rodriguez each cleared outright waivers and have been assigned to Triple-A Tucson.
San Diego outfielder Carlos Quentin was an early scratch from Friday's lineup with irritation in his right knee.
In their last 12 road games, D-backs are 8-4 while outscoring opponents 63-40.
The Padres will honor military families, non-profit organizations and Family Readiness Officers as part of Military Family Appreciation Day presented by USAA on Sunday.
In the first inning of games this season, the D-backs have scored 85 runs while allowing 65.